Tirzepatide Weight Loss Guide

Tirzepatide is a compound with dual actions: it functions as a glucagon-like peptide-1 (GLP-1) receptor agonist and a glucose-dependent insulinotropic polypeptide (GIP). It's primarily used for weight management and blood sugar regulation in overweight or obese patients. Additionally, it may help control appetite and food reward signaling in the brain. However, its usage should be determined by your healthcare provider based on individual conditions.

Available Forms and Dosages

Tirzepatide is typically administered via subcutaneous injectables, available in 1mL and 2mL volumes, with a ratio of 0.5mL = 5mg. It should present as a clear solution upon visual inspection, with no visible particles. Compounded forms with Vitamin B12 or B6 may be requested by patients, appearing as a pink transparent liquid.

Usage Instructions

Follow the dosage and administration instructions provided by your pharmacy and prescriber diligently. For injectables, Tirzepatide should be administered via subcutaneous injection. Rotate injection sites to avoid discomfort, typically using the outer area of the upper arm, abdomen, or front of the thigh. Ensure proper hand hygiene and site sanitation before administration. Refrigerate the medication and discard unused portions after 28 days.

What to Do If You Miss a Dose

If you miss a dose within 4 days of the scheduled dose, administer it as soon as possible. However, if more than 4 days have passed, skip the missed dose and resume regular dosing. Avoid taking double doses to compensate for missed ones.

Monitoring and Interactions

Regular monitoring of blood levels and check-ups with your provider are essential. Tirzepatide may interact with other medications, potentially slowing gastric emptying and affecting their efficacy. Consult your healthcare provider to optimize your therapy.

Potential Side Effects

Common side effects include gastrointestinal issues, headache, fatigue, and dizziness. However, if you experience severe symptoms like trouble breathing, neck mass, or vision changes, seek immediate medical attention.

Contraindications and Precautions

Tirzepatide is contraindicated in individuals with hypersensitivity to the medication, history of medullary thyroid cancer, or multiple endocrine neoplasia syndrome type 2 (MEN 2). Pregnant or breastfeeding individuals should avoid Tirzepatide.

Storage and Additional Information

Follow the storage recommendations on your prescription label, storing injectable Tirzepatide refrigerated and protected from light. Do not share this medication with others, keep it out of reach of children and pets, and dispose of unused portions properly.

Consultation and Reporting Side Effects

An Eros provider is available during normal business hours to address any questions or concerns. Side effects can be reported to the FDA at 1-800-FDA-1088.

Disclaimer

This information serves as an educational resource and does not replace professional medical advice. Always consult your healthcare provider before initiating or modifying any treatment regimen.

References:

  1. Clinical Resource, Comparison of GLP-1 Agonists. Pharmacist's Letter/Prescriber's Letter. August 2019.

  2. Tirzepatide. Lexi-Drugs. Lexicomp. Wolters Kluwer Health, Inc. Riverwoods, IL. Available at: http:/ /online.lexi.com. Accessed December 2022.

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